Improve the appearance of fine lines and wrinkles.* Restylane Refyne will target superficial laugh lines around the nose and mouth.*

The laugh lines that Restylane Refyne targets include the nasolabial folds, the lines that run from the nose to the corners of your mouth and marionette lines that run vertically from the lower corner of the mouth down to the chin.*

Restylane Refyne is specifically developed to give you more of a natural look, providing results that were thought to be impossible.* The hyaluronic acid within the gel filler utilizes a new technology called XpresHAn, which allows increased flexibility allowing the filler to move naturally when you move your face.* This results in a soft and natural enhancement that is not puffy, emotionless or stiff.*

Results can last up to 12 months.* Results vary for each individual and your physician may recommend you return for additional treatment every six to eight months to maintain optimal results. Restylane Refyne has been used in Europe under the name Emervel for over six years.

Restylane Refyne

What is it used for:

To help soften fine laugh lines and surface wrinkles (nasolabial folds and marionette lines).*


Natural improvement allows you to maintain real-life expressions like smiling, frowning and puckering your lips while improving the appearance of fine lines.*
For treating more deep set wrinkles of the nasolabial folds and marionette lines, Restylane Defyne may be a better solution.* Talk with a physician to see which filler is best for you. In some cases, your physician may recommend using a combination of fillers to achieve your desired outcome.*

What are the Differences Between Refyne and Defyne?

The gel filler in Refyne is used more at a superficial level and is less firm, while Defyne is injected at a deeper level beneath the skin, targeting the deep set wrinkles.*
Clinical studies show that 97% of subjects were happy with their treatment results and would do it again.*
If you think you would benefit from Restylane Refyne or are curious to learn which facial filler is right for you, contact us to schedule your consultation and one of our physicians will help find a customized treatment plan that will provide you with optimal results based on your aesthetic goals!

*This was a multicenter, noncooperative trial of subjects aged 35-65 years (N=63). Subjects were evaluated based on the perception of the naturalness of facial expressions in motion after 1 month of Restylane Refyne and Restylane Defyne optimal treatment.