Maintain your natural appearance while subtly improving the appearance of fine lines and wrinkles.* Restylane Refyne could be your ideal solution to target superficial laugh lines around the mouth and nose.*

The laugh lines that are targeted with Restylane Refyne include nasolabial folds, the lines that run vertically from your nose to the outer corners of your mouth and marionette lines that run vertically from the lower corner of the mouth down to the chin.*

Restylane Refyne is specifically developed to give you a more natural-looking result than previously thought possible.* The hyaluronic acid within the gel filler utilizes a new technology called XpresHAn, which allows increased flexibility allowing the filler to move naturally when you move your face.* This results in a soft and natural enhancement that is not puffy, emotionless or stiff.*

Results can last up to 12 months.* Results vary for each individual and your physician may recommend you return for additional treatment every six to eight months to maintain optimal results. Restylane Refyne has been used in Europe under the name Emervel for over six years.

Restylane Refyne

What is it used for:

To help soften fine laugh lines and surface wrinkles (nasolabial folds and marionette lines).*


Natural improvement allows you to maintain real-life expressions like smiling, frowning and puckering your lips while improving the appearance of fine lines.*
For treating more deep set wrinkles of the nasolabial folds and marionette lines, Restylane Defyne may be a better solution.* Talk with a physician to see which filler is best for you. In some cases, your physician may recommend using a combination of fillers to achieve your desired outcome.*

How are Refyne and Defyne different?

The gel filler in Refyne is less firm and is used at a more superficial level, while Defyne is intended to target the deep set wrinkles and is injected at a deeper level beneath the skin.*
Clinical study results show that 97% of subjects were satisfied with their treatment results and would do the treatment again.*
If you think you would benefit from Restylane Refyne or are curious to learn which facial filler is right for you, contact us to schedule your consultation and one of our physicians will help find a customized treatment plan that will provide you with optimal results based on your aesthetic goals!

*This was a multicenter, noncooperative trial of subjects aged 35-65 years (N=63). Subjects were evaluated based on the perception of the naturalness of facial expressions in motion after 1 month of Restylane Refyne and Restylane Defyne optimal treatment.